PacBio Sequel


The PacBio Sequel

We have a PacBio Sequel sequencer which typically generates several hundred thousand ~3 kbp circular consensus sequences (CCS) of high quality sequence approaching that of an Illumina short read sequencer The output is supplied as standard zip compressed Fastq, fasta or unaligned BAM files. We have had several success de novo assembling bacterial genomes consisting of a single contig per chromosome. We have also developed pipelines to sequence and detect variants in very repetitive GC rich amplicons, which can't be easily sequenced with Sangar or Illumina sequencing